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Risperdal (Risperidone)

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Risperdal is a medication with highly developed components which is taken in treatment of serious disorders such as bipolar disorder, mania, schizophrenia, and its symptoms. Risperdal can also be helpful for patients aged 5-16 with autism. Risperdal operates by giving brains balance and mental stability.

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Also known as:  Risperidone.


Risperdal is found by professionals of medicine to combat mental disorders (bipolar disorder, mania, schizophrenia and for patients aged 5-16 with autism). Target of Risperdal is to control and keep brain's balance. Risperdal operates by giving brains balance and mental stability.

Risperdal is atypical antipsychotic.

Risperdal is also known as Risperidone, Risdone.

Generic name of Risperdal is Risperidone.

Brand names of Risperdal are Risperdal, Risperdal Consta, Risperdal M-Tab.


Risperdal is available in tablets (1 mg, 2 mg, 3 mg, 4 mg), liquid forms and in orally disintegrating tablets.

You should take it by mouth with meals of without it. Take it with water.

It is better to take Risperdal every day at the same time once or twice a day.

Risperdal can be given to patients aged 5-16 with autism.

Try to avoid drinking cola or tea together with Risperdal.

If you want to achieve most effective results do not stop taking Risperdal suddenly.


If you overdose Risperdal and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Risperdal overdosage: muscle spasms, fever, fainting, sweating, convulsions, irregular or fast heartbeat, dizziness, feeling drowsy, blurred vision, upset stomach.


Store at room temperature between 15 to 25 degrees C (59 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Risperdal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Risperdal if you are allergic to Risperdal components.

Be careful with Risperdal if you're pregnant or you plan to have a baby, or you are a nursing mother.

Try to avoid drinking cola or tea together with Risperdal.

Try to avoid the state of being overheated.

Try to be careful with Risperdal usage in case of having liver, heart or kidney disease, seizures, Parkinson's disease, breast cancer, diabetes, angina.

Try to be careful with Risperdal usage in case of taking medications as valproic acid (Depakote, Depakene), antidepressants, paroxetine (Paxil), low blood pressure medicines, ranitidine (Zantac), clozapine (Clozaril), carbamazepine (Tegretol), Parkinson's Disease medicines as bromocriptine (Parlodel), pergolide (Permax), levodopa (Sinemet, Atamet, Dopar, Larodopa), ropinirole (Requip), pramipexole (Mirapex).

Elderly patients who are over 65 years should be very careful with Risperdal dosage.

Try to avoid medications caused drowsiness.

Avoid alcohol.

Be careful if you are going to have a surgery.

Avoid machine driving.

Do not stop take it suddenly.

risperdal normal dosage

Patients stabilized on compressed risperidone tablets transitioned to the equivalent dose of orally disintegrating risperidone tablets with continued maintenance of effect, no decompensation and with minimal side effects.

risperdal reviews schizophrenia

Antipsychotics, noradrenergic agents and HRT/CBIT are effective in reducing tics in children and young people with TS. The balance of benefits and harms favours the most commonly used medications: risperidone (Risperdal(®), Janssen), clonidine and aripiprazole (Abilify(®), Otsuka). Larger and better-conducted trials addressing important clinical uncertainties are required. Further research is needed into widening access to behavioural interventions through use of technology including mobile applications ('apps') and video consultation.

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This laboratory developed a simple and efficient solid-phase extraction method that is combined with high-performance liquid chromatography for rapid and precise therapeutic monitoring of risperidone (Risperdal) in blood concentrations. The solid-phase extraction uses a mixed bed column. Sensitivity of the chromatographic method is 0.5 ng/ml (180 pmol/ml) of drug in serum, and separations can be performed in a 15-minute chromatographic run. Advantages of this approach include enhanced speed, sensitivity, and efficiency. A high level of sensitivity may be achieved because of the absence of interference from other drugs, metabolites, or serum components.

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The 90% CI for the geometric means ratios (test/reference) of the log-trasformed Cmax, AUC0-t and AUC0-inf of risperidone and its major active metabolite were within the bioequivalence acceptance criteria of 80% - 125% of the US-FDA.

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Patients with psychoses/schizophrenia using atypical antipsychotics in tablet form perceive generic versions of their antipsychotics as being significantly different. This perceived difference lowers their intention of continuing to take the medication, thus possibly jeopardizing treatment outcome. Caution with the generic substitution of atypical antipsychotics in the pharmacy is therefore recommended. Generic substitution should take place only with the knowledge and agreement of the psychiatrist and the patient.

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This article will briefly familiarize the reader with the positive and negative signs and with the symptoms of Schizophrenia. After describing these signs and symptoms, the atypical anti-psychotic medications of Risperidone, Olanzapine and Clozapine will be reviewed as to their pharmacodynamics, dosages, and side effects in treating of these sign and symptoms. Within the scope of practice for advance practice nurses, the care being rendered and the implementation of those atypical drugs will be described. Thanks to their educational and clinical background, the advanced practice nurses find themselves in a unique set of circumstances to positively contribute in the treatment and maintenance of Schizophrenia.

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A randomized, 2-treatment, 2-period, 2-sequence, single dose, crossover with a washout period of 2 weeks, was conducted in 24 healthy Thai male volunteers. Blood samples were collected at 0, 0.25, 0.5, 0.75, 1, 1.25, 1.5, 1.75, 2, 2.5, 3, 3.5, 4, 5, 6, 8, 10, 12, 24, 36, 48, 72 and 96 h following drug administration. Plasma concentrations of risperidone and 9-hydroxyrisperidone were determined using a validated LC-MS-MS method. The pharmacokinetic parameters of risperidone and 9-hydroxyrisperidone were determined using a non-compartmental model.

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The patient was referred for further medical investigation, as he was demonstrating signs suggestive of a psychiatric disorder. The patient was diagnosed with schizophrenia by a psychiatrist and was prescribed Risperdal.

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According to bioequivalence tests suggested by the Food and Drug Administration (FDA) of the United States (90% confidence interval for the difference of long transformed mean pharmacokinetic parameters), the formulations Risperdal and Spiron, cannot be considered interchangeable.

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Of the respondents, 73% stated that they would be unlikely to take a generic antipsychotic if their pharmacist were to substitute it. Providing patients with a short explanation had a significantly positive effect on their intention to take a generic version; however, overall, the patients' intention to take the generic antipsychotic lay well below a neutral midpoint.

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To meet the requirements for marketing a new generic product, this study was designed to compare the pharmacokinetic properties and bioequivalence of two 2 mg tablet formulations of risperidone: a newly developed generic formulation (test) and a branded formulation (reference) in healthy adult male Chinese volunteers.

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PP-LAI dominated the other two drugs, as it had a lower overall cost and superior clinical outcomes, making it the preferred choice. Using PP-LAI in place of RIS-LAI for chronic relapsing schizophrenia would reduce the overall costs of care for the healthcare system.

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Risperidone (Risperdal) is a recently released novel antipsychotic medication. It is different from the conventional neuroleptics, such as haloperidol, as it has both serotinergic and dopaminergic activity. It has a more tolerable side-effect profile compared with other antipsychotic medications. We review the literature regarding the side effects of risperidone use, describe a case of overdose with risperidone, and discuss the clinical sequelae and management of such an overdose.

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risperdal 3mg medication 2015-08-04

The objective of the study was to compare the bioavailability Anafranil Missed Dose of a generic oral solution of risperidone (Test formulation) and Risperdal tablets (Reference formulation). Both formulations contained 1 mg risperidone per dosing unit.

risperdal good reviews 2017-07-13

Solid SELF of risperidone with improved dissolution and Zetia Renal Dosing digestion profile was successfully prepared using Neusilin® US2 as an adsorbent carrier.

risperdal 40 mg 2016-12-14

Three studies were found that satisfied selection criteria. These studies compared haloperidol with risperidone, olanzapine, and placebo in the management of delirium and in the incidence of adverse drug reactions. Decrease in delirium scores were not significantly different comparing the effect of low dose haloperidol (< 3.0 mg per day) with the atypical antipsychotics olanzapine and risperidone (Odds ratio 0.63 (95% CI 10.29 - 1.38; p = 0.25). Low dose haloperidol did not have a higher incidence of adverse effects than the atypical antipsychotics. High dose haloperidol (> 4.5 mg per day) in one study was associated with an increased incidence of extrapyramidal adverse effects, compared with olanzapine. Low dose haloperidol decreased the severity and duration of delirium in post-operative patients, although not the incidence of delirium, compared to placebo controls in one study. There were no controlled Protonix Loading Dose trials comparing quetiapine with haloperidol.

risperdal dissolving tablet 2015-11-20

As part of a long-term management strategy aimed at improving treatment adherence in schizophrenic patients, RLAI was prescribed to a wide spectrum of patients with an acute episode of schizophrenia during hospitalization and at the time of discharge from emergency/acute care facilities. RLAI was well tolerated in the study population Finasteride Generic Propecia and the overall impression of patients, primary caregivers and relatives to RLAI therapy was positive.

risperdal tablet pictures 2016-04-02

To estimate changes Omnicef Liquid Dosing in resource usage, hospitalization rates, and costs in actual practice in Sweden for schizophrenia patients after switching to long-acting injectable risperidone (Risperdal Consta).

risperdal generic name 2016-04-09

Bioequivalence between the generic 1 mg/ml risperidone solution and the originator tablet formulation was not proven in this Flagyl 500mg Tab study.

risperdal 20 mg 2015-12-22

Long-acting risperidone is effective and generally well tolerated in patients with schizophrenia, including those patients with stable symptoms Luvox Normal Dosage . Long-acting risperidone is the first atypical antipsychotic available in a formulation which offers a sustained, steady release of drug and is thus an attractive, new option in the treatment of patients with schizophrenia.

risperdal high dosage 2017-09-30

Long-acting injectable antipsychotic formulations of conventional antipsychotics were developed to address the problem of partial adherence among patients with schizophrenia. Injection site pain, other skin reactions and patient satisfaction with treatment were assessed in two large, multicentre studies of long-acting injectable risperidone (Risperdal CONSTA, Janssen Pharmaceutica Products, Titusville, New Jersey, USA), the first available long-acting atypical antipsychotic agent. Patients rated injection site pain using a 100-mm Visual Analogue Scale (VAS), and investigators rated injection site pain, redness, swelling and induration. Patient satisfaction with treatment was assessed with the Drug Attitude Inventory (DAI). VAS pain ratings were low at all visits across all doses in both studies, and decreased from first to final injection. In the 12-week, double-blind study, mean +/- SD VAS scores at the first and final injections were 15.6 +/- 20.7 and 12.5 +/- 18.3 for placebo-treated patients, and 11.8 +/- 14.4 (first) and 10.0 +/- 12.4 (final) for 25 mg; 16.3+/-21.9 (first) and 13.6 +/- 21.7 (final) for 50 mg; and 16.0 +/- 17.9 (first) and 9.6 Ventolin Hfa Dose +/- 16.0 (final, P<0.01) for 75 mg of long-acting risperidone. Mean VAS scores in the 50-week, open-label study at the first and final injection were: 17.9 +/- 22.2 (first) and 9.5 +/- 16.7 (final, P<0.0001) for 25 mg; 18.1 +/- 19.7 (first) and 10.4 +/- 14.8 (final, P<0.0001) for 50 mg; and 18.5 +/- 21.6 (first) and 13.6 +/- 19.9 (final, P = 0.0001) for 75 mg of long-acting risperidone. Overall, there was no or minimal injection site pain and skin reactions were rare. Mean DAI ratings were available for the 50-week study and indicated high patient satisfaction throughout the trial (baseline = 7.30; endpoint = 7.70; P<0.0001 versus baseline). These findings may positively affect patient and clinician attitudes towards long-term therapy with long-acting injectable risperidone.

risperdal 8 mg 2015-02-23

The two risperidone formulations are bioequivalent. The test formulation may be used for generic substitution where applicable.

risperdal recommended dosage 2016-06-29

Risperidone is an atypical anti-psychotic, available in various formulations.

risperdal 5 mg 2015-03-07

The classical clinical picture of antiphospholipid antibody syndrome (APS) is characterized by venous and arterial thrombosis, fetal losses and thrombocytopenia in the presence of anticardiolipin antibodies and/or lupus anticoagulant. APS can occur either as a primary disorder or secondary to a connective tissue disease, most frequently systemic lupus erythematosus. Central nervous system involvement is one of the most prominent clinical manifestations of APS, and includes thrombotic events, psychiatric features and a variety of other non-thrombotic neurological syndromes. We present a 9-year-old Saudi girl who developed psychotic illness without thrombotic manifestations. Autoantibodies against cardiolipin were persistent and strongly positive while antinuclear antibodies and antibodies against double-stranded DNA was absent. Her brain computed tomography, magnetic resonance imaging, magnetic resonance arteriography and magnetic resonance venography all were normal. There was no evidence of infection, drug intake or connective tissue disorders, So a diagnosis of primary APS was likely. Starting on antipsychotics only was unsatisfactory and marked improvement occurred after combined treatment with antidepressants (imipramine 10 mg and risperdal 0.2 mg, both once daily), small-dose aspirin (100 mg) and hydroycloroquine (100 mg) both once daily. Unfortunately aspirin was stopped by the family and 5 months later she developed right axillary vein thrombosis. This case presented psychotic illness. Investigations revealed the presence of anticardiolipin antibodies without a thromboembolic picture, mimicking Hughes syndrome but not fulfilling the criteria needed for the diagnosis. Thus, psychosis should be appreciated as a presenting symptom for primary APS and combined treatment with antipsychotics, aspirin and antimalarials is recommended.

overdose risperdal consta 2015-12-11

The 90% confidence intervals for Test/Reference ratios of the pharmacokinetic parameters (Cmax, AUC0-t and AUC0-∞) of both risperidone and its active metabolite (9-hydroxyrisperidone) fell within the acceptable bioequivalence range (80 - 125%) according to ASEAN guideline.

risperdal online 2016-03-26

It has been suggested that atypical antipsychotic drugs (A-APDs) other than clozapine may be effective to improve positive symptoms in some patients with treatment resistant schizophrenia (TRS), if both the dose is higher, and the duration of the trial longer, than those which have been ineffective in non-TRS (NTRS) patients. This hypothesis was tested with long acting injectable risperidone (Risperdal Consta®, RLAI). One hundred sixty TRS patients selected for persistent moderate-severe delusions or hallucinations, or both, were randomized to RLAI, 50 or 100mg biweekly, in a six month, outpatient, double-blind, multicenter trial. We hypothesized that RLAI, 100mg, would be more effective than RLAI, 50mg. However, both doses produced clinically significant and equivalent improvement in PANSS Total, Positive, and Negative subscale scores, as well as key cognitive, global and functional measures, with increasing response during the course of the study, confirming the value of longer clinical trial duration for patients with TRS, but not superiority of the higher dose. The overall response rate was comparable to that previously reported for clozapine and high dose olanzapine, another A-APD, in TRS. Both doses of RLAI were equally well tolerated, producing minimal extrapyramidal side effects and few drop outs. Plasma levels of the active moiety, risperidone+9-hydroxyrisperidone, during treatment with RLAI 100mg, were comparable to those for 6-8 mg/day oral risperidone, which have not been effective in TRS. Further study of RLAI, ≥ 50-100mg biweekly, should compare it with clozapine and oral risperidone in TRS, with duration of treatment ≥ six months.

risperdal 4mg tab 2017-03-19

The findings are limited by the lack of a parallel control treatment, such as with oral risperidone or another antipsychotic, lack of blinded assessments, and a moderate number of subjects. Nevertheless, the findings add to indications that RLAI can be an effective and well-tolerated treatment-option for chronically psychotic patients.

risperdal max dose 2016-12-08

To review the efficacy and tolerability of risperidone as treatment for mania.